MKLN1-AMTN Fusion FISH Probe
The MKLN1-AMTN Fusion FISH Probe is used to confirm a fusion of the MKLN1 and AMTN genes. The fusion of the MKLN1 and AMTN genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MKLN1-AMTN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-RERE | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-REOR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-REGO | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-REGR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-REAQ | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-ORRE | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-OROR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-ORGO | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-ORAQ | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GORE | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GOOR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GOGO | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GOGR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GOAQ | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GRRE | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GROR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GRGO | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GRGR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-GRAQ | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-AQRE | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-AQOR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-AQGO | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-AQGR | 20 (40 μL) | 200 μL |
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| MKLN1-AMTN-20-AQAQ | 20 (40 μL) | 200 μL |
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MKLN1 Gene Summary
Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]
Gene Name: Muskelin 1
Chromosome: CHR7: 130794854 -131181398
Locus: 7q32.3
AMTN Gene Summary
The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM, Mar 2008]
Gene Name: Amelotin
Chromosome: CHR4: 71384297 -71398459
Locus: 4q13.3
Gene Diseases
The MKLN1 AMTN Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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