MKL2-SCNN1B Fusion FISH Probe
The MKL2-SCNN1B Fusion FISH Probe is used to confirm a fusion of the MKL2 and SCNN1B genes. The fusion of the MKL2 and SCNN1B genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MKL2-SCNN1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-RERE | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-REOR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-REGO | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-REGR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-REAQ | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-ORRE | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-OROR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-ORGO | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GORE | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GOOR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GOGO | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GOGR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GRRE | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GROR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GRGO | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GRGR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-AQRE | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-AQOR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-AQGO | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-AQGR | 20 (40 μL) | 200 μL |
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| MKL2-SCNN1B-20-AQAQ | 20 (40 μL) | 200 μL |
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SCNN1B Gene Summary
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009]
Gene Name: Sodium Channel Epithelial 1 Beta Subunit
Chromosome: CHR16: 23313590 -23392620
Locus: 16p12.2
MKL2 Gene Summary
The MKL1/myocardin Like 2 (MKL2) gene is located on chr16 :14165195-14360630 at 16p13.12.
Gene Name: MKL1/myocardin Like 2
Chromosome: CHR16: 14165195 -14360630
Locus: 16p13.12
Gene Diseases
The MKL2 SCNN1B Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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