MITF-FOXP1 Fusion FISH Probe
The MITF-FOXP1 Fusion FISH Probe is used to confirm a fusion of the MITF and FOXP1 genes. The fusion of the MITF and FOXP1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MITF-FOXP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MITF-FOXP1-20-AQAQ | 20 (40 μL) | 200 μL |
|
MITF Gene Summary
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
Gene Name: Melanogenesis Associated Transcription Factor
Chromosome: CHR3: 69788585 -70017488
Locus: 3p13
FOXP1 Gene Summary
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box P1
Chromosome: CHR3: 71004735 -71633140
Locus: 3p13
Gene Diseases
The MITF FOXP1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|