MIPOL1-NPAS3 Fusion FISH Probe
The MIPOL1-NPAS3 Fusion FISH Probe is used to confirm a fusion of the MIPOL1 and NPAS3 genes. The fusion of the MIPOL1 and NPAS3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MIPOL1-NPAS3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-RERE | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-REOR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-REGO | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-REGR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-REAQ | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-ORRE | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-OROR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-ORGO | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-ORAQ | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GORE | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GOOR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GOGO | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GOGR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GOAQ | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GRRE | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GROR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GRGO | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GRGR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-GRAQ | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-AQRE | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-AQOR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-AQGO | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-AQGR | 20 (40 μL) | 200 μL |
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| MIPOL1-NPAS3-20-AQAQ | 20 (40 μL) | 200 μL |
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NPAS3 Gene Summary
This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Name: Neuronal PAS Domain Protein 3
Chromosome: CHR14: 33408458 -34273382
Locus: 14q13.1
MIPOL1 Gene Summary
This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2010]
Gene Name: Mirror-image Polydactyly 1
Chromosome: CHR14: 37667117 -38020464
Locus: 14q13.3-q21.1
Gene Diseases
The MIPOL1 NPAS3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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