MINK1-USO1 Fusion FISH Probe
The MINK1-USO1 Fusion FISH Probe is used to confirm a fusion of the MINK1 and USO1 genes. The fusion of the MINK1 and USO1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MINK1-USO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-RERE | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-REOR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-REGO | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-REGR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-REAQ | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-ORRE | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-OROR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-ORGO | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GORE | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GOOR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GOGO | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GOGR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GRRE | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GROR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GRGO | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GRGR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-AQRE | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-AQOR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-AQGO | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-AQGR | 20 (40 μL) | 200 μL |
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| MINK1-USO1-20-AQAQ | 20 (40 μL) | 200 μL |
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USO1 Gene Summary
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Name: USO1 Vesicle Transport Factor
Chromosome: CHR4: 76649828 -76735366
Locus: 4q21.1
MINK1 Gene Summary
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016]
Gene Name: Misshapen Like Kinase 1
Chromosome: CHR17: 4736634 -4801356
Locus: 17p13.2
Gene Diseases
The MINK1 USO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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