MIF4GD-SDK2 Fusion FISH Probe
The MIF4GD-SDK2 Fusion FISH Probe is used to confirm a fusion of the MIF4GD and SDK2 genes. The fusion of the MIF4GD and SDK2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MIF4GD-SDK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-RERE | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-REOR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-REGO | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-REGR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-REAQ | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-ORRE | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-OROR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-ORGO | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GORE | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GOOR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GOGO | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GOGR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GRRE | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GROR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GRGO | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GRGR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-AQRE | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-AQOR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-AQGO | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-AQGR | 20 (40 μL) | 200 μL |
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| MIF4GD-SDK2-20-AQAQ | 20 (40 μL) | 200 μL |
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SDK2 Gene Summary
The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Name: Sidekick Cell Adhesion Molecule 2
Chromosome: CHR17: 71330522 -71640227
Locus: 17q25.1
MIF4GD Gene Summary
This gene encodes a protein which interacts with the N-terminus of the stem-loop binding protein (SLBP) and the 3' end of histone mRNA. This interaction facilitates the activation of histone mRNA translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Gene Name: MIF4G Domain Containing
Chromosome: CHR17: 73262309 -73267311
Locus: 17q25.1
Gene Diseases
The MIF4GD SDK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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