MID1-S100A2 Fusion FISH Probe
The MID1-S100A2 Fusion FISH Probe is used to confirm a fusion of the MID1 and S100A2 genes. The fusion of the MID1 and S100A2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MID1-S100A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-RERE | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-REOR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-REGO | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-REGR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-REAQ | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-ORRE | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-OROR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-ORGO | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GORE | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GOOR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GOGO | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GOGR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GRRE | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GROR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GRGO | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GRGR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-AQRE | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-AQOR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-AQGO | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-AQGR | 20 (40 μL) | 200 μL |
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| MID1-S100A2-20-AQAQ | 20 (40 μL) | 200 μL |
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MID1 Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
Gene Name: Midline 1
Chromosome: CHRX: 10413349 -10851809
Locus: Xp22.2
S100A2 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008]
Gene Name: S100 Calcium Binding Protein A2
Chromosome: CHR1: 153533584 -153538306
Locus: 1q21.3
Gene Diseases
The MID1 S100A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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