MIB1-MYO5B Fusion FISH Probe
The MIB1-MYO5B Fusion FISH Probe is used to confirm a fusion of the MIB1 and MYO5B genes. The fusion of the MIB1 and MYO5B genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MIB1-MYO5B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-RERE | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-REOR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-REGO | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-REGR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-REAQ | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-ORRE | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-OROR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-ORGO | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-ORAQ | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GORE | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GOOR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GOGO | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GOGR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GOAQ | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GRRE | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GROR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GRGO | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GRGR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-GRAQ | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-AQRE | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-AQOR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-AQGO | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-AQGR | 20 (40 μL) | 200 μL |
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| MIB1-MYO5B-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO5B Gene Summary
The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009]
Gene Name: Myosin VB
Chromosome: CHR18: 47349155 -47721451
Locus: 18q21.1
MIB1 Gene Summary
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]
Gene Name: Mindbomb E3 Ubiquitin Protein Ligase 1
Chromosome: CHR18: 19321544 -19450912
Locus: 18q11.2
Gene Diseases
The MIB1 MYO5B Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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