MIB1-HLTF Fusion FISH Probe
The MIB1-HLTF Fusion FISH Probe is used to confirm a fusion of the MIB1 and HLTF genes. The fusion of the MIB1 and HLTF genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MIB1-HLTF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-RERE | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-REOR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-REGO | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-REGR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-REAQ | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-ORRE | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-OROR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-ORGO | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-ORAQ | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GORE | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GOOR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GOGO | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GOGR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GOAQ | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GRRE | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GROR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GRGO | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GRGR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-GRAQ | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-AQRE | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-AQOR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-AQGO | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-AQGR | 20 (40 μL) | 200 μL |
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| MIB1-HLTF-20-AQAQ | 20 (40 μL) | 200 μL |
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HLTF Gene Summary
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008]
Gene Name: Helicase Like Transcription Factor
Chromosome: CHR3: 148747903 -148804341
Locus: 3q24
MIB1 Gene Summary
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]
Gene Name: Mindbomb E3 Ubiquitin Protein Ligase 1
Chromosome: CHR18: 19321544 -19450912
Locus: 18q11.2
Gene Diseases
The MIB1 HLTF Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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