MGST1-COL27A1 Fusion FISH Probe
The MGST1-COL27A1 Fusion FISH Probe is used to confirm a fusion of the MGST1 and COL27A1 genes. The fusion of the MGST1 and COL27A1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MGST1-COL27A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-RERE | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-REOR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-REGO | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-REGR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-REAQ | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-ORRE | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-OROR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-ORGO | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GORE | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GOOR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GOGO | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GOGR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GRRE | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GROR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GRGO | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GRGR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-AQRE | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-AQOR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-AQGO | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-AQGR | 20 (40 μL) | 200 μL |
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| MGST1-COL27A1-20-AQAQ | 20 (40 μL) | 200 μL |
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MGST1 Gene Summary
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: Microsomal Glutathione S-transferase 1
Chromosome: CHR12: 16500075 -16517344
Locus: 12p12.3
COL27A1 Gene Summary
This gene encodes a member of the fibrillar collagen family, and plays a role during the calcification of cartilage and the transition of cartilage to bone. The encoded protein product is a preproprotein. It includes an N-terminal signal peptide, which is followed by an N-terminal propetide, mature peptide and a C-terminal propeptide. The N-terminal propeptide contains thrombospondin N-terminal-like and laminin G-like domains. The mature peptide is a major triple-helical region. The C-terminal propeptide, also known as COLFI domain, plays crucial roles in tissue growth and repair. Mutations in this gene cause Steel syndrome. Alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Sep 2014]
Gene Name: Collagen Type XXVII Alpha 1 Chain
Chromosome: CHR9: 116918230 -117072975
Locus: 9q32
Gene Diseases
The MGST1 COL27A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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