MGAT4B-RNF130 Fusion FISH Probe
The MGAT4B-RNF130 Fusion FISH Probe is used to confirm a fusion of the MGAT4B and RNF130 genes. The fusion of the MGAT4B and RNF130 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MGAT4B-RNF130-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-RERE | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-REOR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-REGO | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-REGR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-REAQ | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-ORRE | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-OROR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-ORGO | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-ORAQ | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GORE | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GOOR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GOGO | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GOGR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GOAQ | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GRRE | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GROR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GRGO | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GRGR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-GRAQ | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-AQRE | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-AQOR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-AQGO | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-AQGR | 20 (40 μL) | 200 μL |
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| MGAT4B-RNF130-20-AQAQ | 20 (40 μL) | 200 μL |
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MGAT4B Gene Summary
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008]
Gene Name: Mannosyl (alpha-1,3-)-glycoprotein Beta-1,4-N-acetylglucosaminyltransferase, Isozyme B
Chromosome: CHR5: 179224597 -179233952
Locus: 5q35.3
RNF130 Gene Summary
The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Ring Finger Protein 130
Chromosome: CHR5: 179382473 -179499109
Locus: 5q35.3
Gene Diseases
The MGAT4B RNF130 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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