MGAT4B-ETF1 Fusion FISH Probe
The MGAT4B-ETF1 Fusion FISH Probe is used to confirm a fusion of the MGAT4B and ETF1 genes. The fusion of the MGAT4B and ETF1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MGAT4B-ETF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-RERE | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-REOR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-REGO | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-REGR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-REAQ | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-ORRE | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-OROR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-ORGO | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GORE | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GOOR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GOGO | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GOGR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GRRE | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GROR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GRGO | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GRGR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-AQRE | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-AQOR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-AQGO | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-AQGR | 20 (40 μL) | 200 μL |
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| MGAT4B-ETF1-20-AQAQ | 20 (40 μL) | 200 μL |
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ETF1 Gene Summary
This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]
Gene Name: Eukaryotic Translation Termination Factor 1
Chromosome: CHR5: 137841783 -137878932
Locus: 5q31.2
MGAT4B Gene Summary
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008]
Gene Name: Mannosyl (alpha-1,3-)-glycoprotein Beta-1,4-N-acetylglucosaminyltransferase, Isozyme B
Chromosome: CHR5: 179224597 -179233952
Locus: 5q35.3
Gene Diseases
The MGAT4B ETF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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