MFHAS1-ZFAT Fusion FISH Probe
The MFHAS1-ZFAT Fusion FISH Probe is used to confirm a fusion of the MFHAS1 and ZFAT genes. The fusion of the MFHAS1 and ZFAT genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MFHAS1-ZFAT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-RERE | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-REOR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-REGO | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-REGR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-REAQ | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-ORRE | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-OROR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-ORGO | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-ORAQ | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GORE | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GOOR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GOGO | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GOGR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GOAQ | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GRRE | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GROR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GRGO | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GRGR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-GRAQ | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-AQRE | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-AQOR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-AQGO | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-AQGR | 20 (40 μL) | 200 μL |
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| MFHAS1-ZFAT-20-AQAQ | 20 (40 μL) | 200 μL |
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MFHAS1 Gene Summary
Identified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH. [provided by RefSeq, Jul 2008]
Gene Name: Malignant Fibrous Histiocytoma Amplified Sequence 1
Chromosome: CHR8: 8641998 -8751131
Locus: 8p23.1
ZFAT Gene Summary
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Gene Name: Zinc Finger And AT-hook Domain Containing
Chromosome: CHR8: 135490030 -135725292
Locus: 8q24.22
Gene Diseases
The MFHAS1 ZFAT Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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