METTL5-MERTK Fusion FISH Probe
The METTL5-MERTK Fusion FISH Probe is used to confirm a fusion of the METTL5 and MERTK genes. The fusion of the METTL5 and MERTK genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| METTL5-MERTK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-RERE | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-REOR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-REGO | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-REGR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-REAQ | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-ORRE | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-OROR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-ORGO | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-ORAQ | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GORE | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GOOR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GOGO | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GOGR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GOAQ | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GRRE | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GROR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GRGO | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GRGR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-GRAQ | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-AQRE | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-AQOR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-AQGO | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-AQGR | 20 (40 μL) | 200 μL |
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| METTL5-MERTK-20-AQAQ | 20 (40 μL) | 200 μL |
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MERTK Gene Summary
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]
Gene Name: MER Proto-oncogene, Tyrosine Kinase
Chromosome: CHR2: 112656190 -112786945
Locus: 2q13
METTL5 Gene Summary
The Methyltransferase Like 5 (METTL5) gene is located on chr2 :170668267-170681353 at 2q31.1.
Gene Name: Methyltransferase Like 5
Chromosome: CHR2: 170668267 -170681353
Locus: 2q31.1
Gene Diseases
The METTL5 MERTK Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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