METTL4-STXBP5L Fusion FISH Probe
The METTL4-STXBP5L Fusion FISH Probe is used to confirm a fusion of the METTL4 and STXBP5L genes. The fusion of the METTL4 and STXBP5L genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| METTL4-STXBP5L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-RERE | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-REOR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-REGO | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-REGR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-REAQ | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-ORRE | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-OROR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-ORGO | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-ORAQ | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GORE | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GOOR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GOGO | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GOGR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GOAQ | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GRRE | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GROR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GRGO | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GRGR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-GRAQ | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-AQRE | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-AQOR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-AQGO | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-AQGR | 20 (40 μL) | 200 μL |
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| METTL4-STXBP5L-20-AQAQ | 20 (40 μL) | 200 μL |
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STXBP5L Gene Summary
The protein encoded by this gene is similar to syntaxin-binding protein 5 and contains ten N-terminal WD40 repeats, four variable region WD40 repeats, and a C-terminal R-SNARE domain. Studies of the orthologous proteins in mouse and rat have shown that the encoded protein may inhibit exocytosis in neurosecretory cells, and may negatively regulate the secretion of insulin. A missense variant in this gene is likely the cause of an infantile-onset neurodegenerative disorder diagnosed in two siblings of consanguineous parents. [provided by RefSeq, Jan 2017]
Gene Name: Syntaxin Binding Protein 5 Like
Chromosome: CHR3: 120627049 -121143608
Locus: 3q13.33
METTL4 Gene Summary
The Methyltransferase Like 4 (METTL4) gene is located on chr18 :2537523-2571489 at 18p11.32.
Gene Name: Methyltransferase Like 4
Chromosome: CHR18: 2537523 -2571489
Locus: 18p11.32
Gene Diseases
The METTL4 STXBP5L Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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