METTL3-SALL2 Fusion FISH Probe
The METTL3-SALL2 Fusion FISH Probe is used to confirm a fusion of the METTL3 and SALL2 genes. The fusion of the METTL3 and SALL2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| METTL3-SALL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-RERE | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-REOR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-REGO | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-REGR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-REAQ | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-ORRE | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-OROR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-ORGO | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GORE | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GOOR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GOGO | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GOGR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GRRE | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GROR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GRGO | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GRGR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-AQRE | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-AQOR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-AQGO | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-AQGR | 20 (40 μL) | 200 μL |
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| METTL3-SALL2-20-AQAQ | 20 (40 μL) | 200 μL |
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SALL2 Gene Summary
This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma. [provided by RefSeq, Jul 2016]
Gene Name: Spalt Like Transcription Factor 2
Chromosome: CHR14: 21989231 -22005337
Locus: 14q11.2
METTL3 Gene Summary
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]
Gene Name: Methyltransferase Like 3
Chromosome: CHR14: 21966281 -21979457
Locus: 14q11.2
Gene Diseases
The METTL3 SALL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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