MEF2D-CD55 Fusion FISH Probe
The MEF2D-CD55 Fusion FISH Probe is used to confirm a fusion of the MEF2D and CD55 genes. The fusion of the MEF2D and CD55 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MEF2D-CD55-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-RERE | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-REOR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-REGO | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-REGR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-REAQ | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-ORRE | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-OROR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-ORGO | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-ORAQ | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GORE | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GOOR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GOGO | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GOGR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GOAQ | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GRRE | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GROR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GRGO | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GRGR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-GRAQ | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-AQRE | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-AQOR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-AQGO | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-AQGR | 20 (40 μL) | 200 μL |
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| MEF2D-CD55-20-AQAQ | 20 (40 μL) | 200 μL |
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CD55 Gene Summary
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014]
Gene Name: CD55 Molecule (Cromer Blood Group)
Chromosome: CHR1: 207494816 -207534311
Locus: 1q32.2
MEF2D Gene Summary
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Gene Name: Myocyte Enhancer Factor 2D
Chromosome: CHR1: 156433518 -156470529
Locus: 1q22
Gene Diseases
The MEF2D CD55 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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