MEF2A-WDR61 Fusion FISH Probe
The MEF2A-WDR61 Fusion FISH Probe is used to confirm a fusion of the MEF2A and WDR61 genes. The fusion of the MEF2A and WDR61 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MEF2A-WDR61-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-RERE | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-REOR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-REGO | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-REGR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-REAQ | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-ORRE | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-OROR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-ORGO | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-ORAQ | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GORE | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GOOR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GOGO | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GOGR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GOAQ | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GRRE | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GROR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GRGO | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GRGR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-GRAQ | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-AQRE | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-AQOR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-AQGO | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-AQGR | 20 (40 μL) | 200 μL |
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| MEF2A-WDR61-20-AQAQ | 20 (40 μL) | 200 μL |
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MEF2A Gene Summary
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Gene Name: Myocyte Enhancer Factor 2A
Chromosome: CHR15: 100106132 -100256629
Locus: 15q26.3
WDR61 Gene Summary
WDR61 is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (Zhu et al., 2005 [PubMed 16024656]).[supplied by OMIM, Mar 2008]
Gene Name: WD Repeat Domain 61
Chromosome: CHR15: 78575577 -78591940
Locus: 15q25.1
Gene Diseases
The MEF2A WDR61 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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