MEF2A-SV2B Fusion FISH Probe
The MEF2A-SV2B Fusion FISH Probe is used to confirm a fusion of the MEF2A and SV2B genes. The fusion of the MEF2A and SV2B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MEF2A-SV2B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-RERE | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-REOR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-REGO | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-REGR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-REAQ | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-ORRE | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-OROR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-ORGO | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-ORAQ | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GORE | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GOOR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GOGO | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GOGR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GOAQ | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GRRE | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GROR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GRGO | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GRGR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-GRAQ | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-AQRE | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-AQOR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-AQGO | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-AQGR | 20 (40 μL) | 200 μL |
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| MEF2A-SV2B-20-AQAQ | 20 (40 μL) | 200 μL |
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MEF2A Gene Summary
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Gene Name: Myocyte Enhancer Factor 2A
Chromosome: CHR15: 100106132 -100256629
Locus: 15q26.3
SV2B Gene Summary
This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. [provided by RefSeq, Sep 2016]
Gene Name: Synaptic Vesicle Glycoprotein 2B
Chromosome: CHR15: 91643181 -91844539
Locus: 15q26.1
Gene Diseases
The MEF2A SV2B Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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