MED4-HTR2A Fusion FISH Probe
The MED4-HTR2A Fusion FISH Probe is used to confirm a fusion of the MED4 and HTR2A genes. The fusion of the MED4 and HTR2A genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED4-HTR2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-RERE | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-REOR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-REGO | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-REGR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-REAQ | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-ORRE | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-OROR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-ORGO | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GORE | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GOOR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GOGO | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GOGR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GRRE | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GROR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GRGO | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GRGR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-AQRE | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-AQOR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-AQGO | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-AQGR | 20 (40 μL) | 200 μL |
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| MED4-HTR2A-20-AQAQ | 20 (40 μL) | 200 μL |
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HTR2A Gene Summary
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Name: 5-hydroxytryptamine Receptor 2A
Chromosome: CHR13: 47407512 -47471169
Locus: 13q14.2
MED4 Gene Summary
This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Mediator Complex Subunit 4
Chromosome: CHR13: 48650091 -48669240
Locus: 13q14.2
Gene Diseases
The MED4 HTR2A Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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