MED29-ADAM18 Fusion FISH Probe
The MED29-ADAM18 Fusion FISH Probe is used to confirm a fusion of the MED29 and ADAM18 genes. The fusion of the MED29 and ADAM18 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED29-ADAM18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-RERE | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-REOR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-REGO | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-REGR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-REAQ | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-ORRE | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-OROR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-ORGO | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GORE | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GOOR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GOGO | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GOGR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GRRE | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GROR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GRGO | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GRGR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-AQRE | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-AQOR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-AQGO | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-AQGR | 20 (40 μL) | 200 μL |
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| MED29-ADAM18-20-AQAQ | 20 (40 μL) | 200 μL |
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ADAM18 Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature sperm surface protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Name: ADAM Metallopeptidase Domain 18
Chromosome: CHR8: 39442086 -39587583
Locus: 8p11.22
MED29 Gene Summary
MED29 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al., 2003 [PubMed 14576168]).[supplied by OMIM, Aug 2009]
Gene Name: Mediator Complex Subunit 29
Chromosome: CHR19: 39881962 -39891203
Locus: 19q13.2
Gene Diseases
The MED29 ADAM18 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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