MED24-NR1D1 Fusion FISH Probe
The MED24-NR1D1 Fusion FISH Probe is used to confirm a fusion of the MED24 and NR1D1 genes. The fusion of the MED24 and NR1D1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED24-NR1D1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-RERE | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-REOR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-REGO | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-REGR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-REAQ | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-ORRE | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-OROR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-ORGO | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GORE | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GOOR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GOGO | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GOGR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GRRE | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GROR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GRGO | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GRGR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-AQRE | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-AQOR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-AQGO | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-AQGR | 20 (40 μL) | 200 μL |
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| MED24-NR1D1-20-AQAQ | 20 (40 μL) | 200 μL |
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NR1D1 Gene Summary
This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013]
Gene Name: Nuclear Receptor Subfamily 1 Group D Member 1
Chromosome: CHR17: 38249036 -38256973
Locus: 17q21.1
MED24 Gene Summary
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Mediator Complex Subunit 24
Chromosome: CHR17: 38175349 -38210889
Locus: 17q21.1
Gene Diseases
The MED24 NR1D1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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