MED24-KRT40 Fusion FISH Probe
The MED24-KRT40 Fusion FISH Probe is used to confirm a fusion of the MED24 and KRT40 genes. The fusion of the MED24 and KRT40 genes has been associated with Ovarian Serous Cystadenocarcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED24-KRT40-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-RERE | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-REOR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-REGO | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-REGR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-REAQ | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-ORRE | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-OROR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-ORGO | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GORE | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GOOR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GOGO | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GOGR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GRRE | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GROR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GRGO | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GRGR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-AQRE | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-AQOR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-AQGO | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-AQGR | 20 (40 μL) | 200 μL |
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| MED24-KRT40-20-AQAQ | 20 (40 μL) | 200 μL |
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MED24 Gene Summary
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Mediator Complex Subunit 24
Chromosome: CHR17: 38175349 -38210889
Locus: 17q21.1
KRT40 Gene Summary
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Gene Name: Keratin 40
Chromosome: CHR17: 39133967 -39143387
Locus: 17q21.2
Gene Diseases
The MED24 KRT40 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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