MED21-PIP5K1C Fusion FISH Probe
The MED21-PIP5K1C Fusion FISH Probe is used to confirm a fusion of the MED21 and PIP5K1C genes. The fusion of the MED21 and PIP5K1C genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED21-PIP5K1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-RERE | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-REOR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-REGO | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-REGR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-REAQ | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-ORRE | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-OROR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-ORGO | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GORE | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GOOR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GOGO | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GOGR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GRRE | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GROR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GRGO | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GRGR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-AQRE | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-AQOR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-AQGO | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-AQGR | 20 (40 μL) | 200 μL |
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| MED21-PIP5K1C-20-AQAQ | 20 (40 μL) | 200 μL |
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MED21 Gene Summary
This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Name: Mediator Complex Subunit 21
Chromosome: CHR12: 27175482 -27182682
Locus: 12p11.23
PIP5K1C Gene Summary
This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010]
Gene Name: Phosphatidylinositol-4-phosphate 5-kinase Type 1 Gamma
Chromosome: CHR19: 3630178 -3700477
Locus: 19p13.3
Gene Diseases
The MED21 PIP5K1C Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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