MED16-POLR2E Fusion FISH Probe
The MED16-POLR2E Fusion FISH Probe is used to confirm a fusion of the MED16 and POLR2E genes. The fusion of the MED16 and POLR2E genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED16-POLR2E-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-RERE | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-REOR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-REGO | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-REGR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-REAQ | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-ORRE | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-OROR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-ORGO | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GORE | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GOOR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GOGO | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GOGR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GRRE | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GROR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GRGO | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GRGR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-AQRE | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-AQOR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-AQGO | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-AQGR | 20 (40 μL) | 200 μL |
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| MED16-POLR2E-20-AQAQ | 20 (40 μL) | 200 μL |
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POLR2E Gene Summary
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Name: RNA Polymerase II Subunit E
Chromosome: CHR19: 1086577 -1095391
Locus: 19p13.3
MED16 Gene Summary
The Mediator Complex Subunit 16 (MED16) gene is located on chr19 :867961-893218 at 19p13.3.
Gene Name: Mediator Complex Subunit 16
Chromosome: CHR19: 867961 -893218
Locus: 19p13.3
Gene Diseases
The MED16 POLR2E Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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