MED14-SRPX Fusion FISH Probe
The MED14-SRPX Fusion FISH Probe is used to confirm a fusion of the MED14 and SRPX genes. The fusion of the MED14 and SRPX genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MED14-SRPX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MED14-SRPX-20-AQAQ | 20 (40 μL) | 200 μL |
|
SRPX Gene Summary
The Sushi Repeat Containing Protein, X-linked (SRPX) gene is located on chrX :38008587-38080177 at Xp11.4.
Gene Name: Sushi Repeat Containing Protein, X-linked
Chromosome: CHRX: 38008587 -38080177
Locus: Xp11.4
MED14 Gene Summary
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008]
Gene Name: Mediator Complex Subunit 14
Chromosome: CHRX: 40508794 -40594804
Locus: Xp11.4
Gene Diseases
The MED14 SRPX Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|