MED13L-TRAFD1 Fusion FISH Probe
The MED13L-TRAFD1 Fusion FISH Probe is used to confirm a fusion of the MED13L and TRAFD1 genes. The fusion of the MED13L and TRAFD1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED13L-TRAFD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-RERE | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-REOR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-REGO | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-REGR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-REAQ | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-ORRE | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-OROR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-ORGO | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GORE | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GOOR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GOGO | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GOGR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GRRE | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GROR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GRGO | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GRGR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-AQRE | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-AQOR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-AQGO | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-AQGR | 20 (40 μL) | 200 μL |
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| MED13L-TRAFD1-20-AQAQ | 20 (40 μL) | 200 μL |
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TRAFD1 Gene Summary
The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009]
Gene Name: TRAF-type Zinc Finger Domain Containing 1
Chromosome: CHR12: 112563348 -112591408
Locus: 12q24.13
MED13L Gene Summary
The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]
Gene Name: Mediator Complex Subunit 13 Like
Chromosome: CHR12: 116396380 -116714991
Locus: 12q24.21
Gene Diseases
The MED13L TRAFD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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