MED13-DDX42 Fusion FISH Probe
The MED13-DDX42 Fusion FISH Probe is used to confirm a fusion of the MED13 and DDX42 genes. The fusion of the MED13 and DDX42 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED13-DDX42-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-RERE | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-REOR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-REGO | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-REGR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-REAQ | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-ORRE | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-OROR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-ORGO | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GORE | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GOOR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GOGO | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GOGR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GRRE | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GROR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GRGO | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GRGR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-AQRE | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-AQOR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-AQGO | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-AQGR | 20 (40 μL) | 200 μL |
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| MED13-DDX42-20-AQAQ | 20 (40 μL) | 200 μL |
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MED13 Gene Summary
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008]
Gene Name: Mediator Complex Subunit 13
Chromosome: CHR17: 60019965 -60142643
Locus: 17q23.2
DDX42 Gene Summary
This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: DEAD-box Helicase 42
Chromosome: CHR17: 61851566 -61896677
Locus: 17q23.3
Gene Diseases
The MED13 DDX42 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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