MECOM-LRRC34 Fusion FISH Probe
The MECOM-LRRC34 Fusion FISH Probe is used to confirm a fusion of the MECOM and LRRC34 genes. The fusion of the MECOM and LRRC34 genes has been associated with Uterine Corpus Endometrial Carcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MECOM-LRRC34-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-RERE | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-REOR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-REGO | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-REGR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-REAQ | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-ORRE | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-OROR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-ORGO | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-ORAQ | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GORE | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GOOR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GOGO | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GOGR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GOAQ | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GRRE | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GROR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GRGO | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GRGR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-GRAQ | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-AQRE | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-AQOR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-AQGO | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-AQGR | 20 (40 μL) | 200 μL |
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| MECOM-LRRC34-20-AQAQ | 20 (40 μL) | 200 μL |
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MECOM Gene Summary
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Name: MDS1 And EVI1 Complex Locus
Chromosome: CHR3: 168801286 -169381563
Locus: 3q26.2
LRRC34 Gene Summary
The Leucine Rich Repeat Containing 34 (LRRC34) gene is located on chr3 :169511215-169530574 at 3q26.2.
Gene Name: Leucine Rich Repeat Containing 34
Chromosome: CHR3: 169511215 -169530574
Locus: 3q26.2
Gene Diseases
The MECOM LRRC34 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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