MDM1-NAV3 Fusion FISH Probe
The MDM1-NAV3 Fusion FISH Probe is used to confirm a fusion of the MDM1 and NAV3 genes. The fusion of the MDM1 and NAV3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MDM1-NAV3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-RERE | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-REOR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-REGO | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-REGR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-REAQ | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-ORRE | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-OROR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-ORGO | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-ORAQ | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GORE | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GOOR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GOGO | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GOGR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GOAQ | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GRRE | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GROR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GRGO | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GRGR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-GRAQ | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-AQRE | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-AQOR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-AQGO | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-AQGR | 20 (40 μL) | 200 μL |
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| MDM1-NAV3-20-AQAQ | 20 (40 μL) | 200 μL |
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MDM1 Gene Summary
This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells, and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. naturally occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Aug 2017]
Gene Name: Mdm1 Nuclear Protein
Chromosome: CHR12: 68688345 -68726161
Locus: 12q15
NAV3 Gene Summary
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008]
Gene Name: Neuron Navigator 3
Chromosome: CHR12: 78225068 -78606790
Locus: 12q21.2
Gene Diseases
The MDM1 NAV3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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