MDM1-ABCC1 Fusion FISH Probe
The MDM1-ABCC1 Fusion FISH Probe is used to confirm a fusion of the MDM1 and ABCC1 genes. The fusion of the MDM1 and ABCC1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MDM1-ABCC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-RERE | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-REOR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-REGO | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-REGR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-REAQ | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-ORRE | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-OROR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-ORGO | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GORE | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GOOR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GOGO | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GOGR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GRRE | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GROR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GRGO | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GRGR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-AQRE | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-AQOR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-AQGO | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-AQGR | 20 (40 μL) | 200 μL |
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| MDM1-ABCC1-20-AQAQ | 20 (40 μL) | 200 μL |
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ABCC1 Gene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
Gene Name: ATP Binding Cassette Subfamily C Member 1
Chromosome: CHR16: 16043433 -16236930
Locus: 16p13.11
MDM1 Gene Summary
This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells, and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. naturally occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Aug 2017]
Gene Name: Mdm1 Nuclear Protein
Chromosome: CHR12: 68688345 -68726161
Locus: 12q15
Gene Diseases
The MDM1 ABCC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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