MDK-PARP1 Fusion FISH Probe
The MDK-PARP1 Fusion FISH Probe is used to confirm a fusion of the MDK and PARP1 genes. The fusion of the MDK and PARP1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MDK-PARP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-RERE | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-REOR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-REGO | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-REGR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-REAQ | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-ORRE | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-OROR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-ORGO | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GORE | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GOOR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GOGO | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GOGR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GRRE | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GROR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GRGO | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GRGR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-AQRE | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-AQOR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-AQGO | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-AQGR | 20 (40 μL) | 200 μL |
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| MDK-PARP1-20-AQAQ | 20 (40 μL) | 200 μL |
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PARP1 Gene Summary
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Gene Name: Poly(ADP-ribose) Polymerase 1
Chromosome: CHR1: 226548391 -226595801
Locus: 1q42.12
MDK Gene Summary
This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]
Gene Name: Midkine
Chromosome: CHR11: 46402617 -46405375
Locus: 11p11.2
Gene Diseases
The MDK PARP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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