MCTP1-CBLB Fusion FISH Probe
The MCTP1-CBLB Fusion FISH Probe is used to confirm a fusion of the MCTP1 and CBLB genes. The fusion of the MCTP1 and CBLB genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MCTP1-CBLB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-RERE | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-REOR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-REGO | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-REGR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-REAQ | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-ORRE | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-OROR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-ORGO | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-ORAQ | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GORE | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GOOR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GOGO | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GOGR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GOAQ | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GRRE | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GROR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GRGO | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GRGR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-GRAQ | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-AQRE | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-AQOR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-AQGO | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-AQGR | 20 (40 μL) | 200 μL |
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| MCTP1-CBLB-20-AQAQ | 20 (40 μL) | 200 μL |
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CBLB Gene Summary
This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections. [provided by RefSeq, Sep 2017]
Gene Name: Cbl Proto-oncogene B
Chromosome: CHR3: 105377108 -105587887
Locus: 3q13.11
MCTP1 Gene Summary
The Multiple C2 And Transmembrane Domain Containing 1 (MCTP1) gene is located on chr5 :94042288-94620279 at 5q15.
Gene Name: Multiple C2 And Transmembrane Domain Containing 1
Chromosome: CHR5: 94042288 -94620279
Locus: 5q15
Gene Diseases
The MCTP1 CBLB Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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