MCM3-GPR110 Fusion FISH Probe
The MCM3-GPR110 Fusion FISH Probe is used to confirm a fusion of the MCM3 and GPR110 genes. The fusion of the MCM3 and GPR110 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MCM3-GPR110-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-RERE | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-REOR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-REGO | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-REGR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-REAQ | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-ORRE | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-OROR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-ORGO | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-ORAQ | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GORE | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GOOR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GOGO | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GOGR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GOAQ | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GRRE | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GROR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GRGO | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GRGR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-GRAQ | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-AQRE | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-AQOR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-AQGO | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-AQGR | 20 (40 μL) | 200 μL |
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| MCM3-GPR110-20-AQAQ | 20 (40 μL) | 200 μL |
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MCM3 Gene Summary
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Minichromosome Maintenance Complex Component 3
Chromosome: CHR6: 52128811 -52149582
Locus: 6p12.2
Gene Diseases
The MCM3 GPR110 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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