MCL1-CTSS Fusion FISH Probe
The MCL1-CTSS Fusion FISH Probe is used to confirm a fusion of the MCL1 and CTSS genes. The fusion of the MCL1 and CTSS genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MCL1-CTSS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MCL1-CTSS-20-AQAQ | 20 (40 μL) | 200 μL |
|
CTSS Gene Summary
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Cathepsin S
Chromosome: CHR1: 150702671 -150738433
Locus: 1q21.3
MCL1 Gene Summary
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
Gene Name: MCL1, BCL2 Family Apoptosis Regulator
Chromosome: CHR1: 150547026 -150552214
Locus: 1q21.2
Gene Diseases
The MCL1 CTSS Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|