MCF2L-LAMA5 Fusion FISH Probe
The MCF2L-LAMA5 Fusion FISH Probe is used to confirm a fusion of the MCF2L and LAMA5 genes. The fusion of the MCF2L and LAMA5 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MCF2L-LAMA5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-RERE | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-REOR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-REGO | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-REGR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-REAQ | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-ORRE | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-OROR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-ORGO | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-ORAQ | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GORE | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GOOR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GOGO | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GOGR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GOAQ | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GRRE | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GROR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GRGO | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GRGR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-GRAQ | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-AQRE | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-AQOR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-AQGO | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-AQGR | 20 (40 μL) | 200 μL |
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| MCF2L-LAMA5-20-AQAQ | 20 (40 μL) | 200 μL |
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LAMA5 Gene Summary
This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]
Gene Name: Laminin Subunit Alpha 5
Chromosome: CHR20: 60884120 -60942368
Locus: 20q13.33
MCF2L Gene Summary
This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: MCF.2 Cell Line Derived Transforming Sequence Like
Chromosome: CHR13: 113623534 -113754053
Locus: 13q34
Gene Diseases
The MCF2L LAMA5 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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