MCF2L-GAS6 Fusion FISH Probe
The MCF2L-GAS6 Fusion FISH Probe is used to confirm a fusion of the MCF2L and GAS6 genes. The fusion of the MCF2L and GAS6 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MCF2L-GAS6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-RERE | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-REOR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-REGO | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-REGR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-REAQ | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-ORRE | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-OROR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-ORGO | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-ORAQ | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GORE | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GOOR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GOGO | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GOGR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GOAQ | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GRRE | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GROR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GRGO | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GRGR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-GRAQ | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-AQRE | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-AQOR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-AQGO | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-AQGR | 20 (40 μL) | 200 μL |
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| MCF2L-GAS6-20-AQAQ | 20 (40 μL) | 200 μL |
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GAS6 Gene Summary
This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014]
Gene Name: Growth Arrest Specific 6
Chromosome: CHR13: 114523521 -114567046
Locus: 13q34
MCF2L Gene Summary
This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: MCF.2 Cell Line Derived Transforming Sequence Like
Chromosome: CHR13: 113623534 -113754053
Locus: 13q34
Gene Diseases
The MCF2L GAS6 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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