MCEE-ANXA4 Fusion FISH Probe
The MCEE-ANXA4 Fusion FISH Probe is used to confirm a fusion of the MCEE and ANXA4 genes. The fusion of the MCEE and ANXA4 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MCEE-ANXA4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-RERE | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-REOR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-REGO | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-REGR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-REAQ | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-ORRE | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-OROR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-ORGO | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-ORAQ | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GORE | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GOOR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GOGO | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GOGR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GOAQ | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GRRE | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GROR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GRGO | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GRGR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-GRAQ | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-AQRE | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-AQOR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-AQGO | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-AQGR | 20 (40 μL) | 200 μL |
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| MCEE-ANXA4-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA4 Gene Summary
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Name: Annexin A4
Chromosome: CHR2: 69969126 -70053596
Locus: 2p13.3
MCEE Gene Summary
The product of this gene catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria. [provided by RefSeq, Jul 2008]
Gene Name: Methylmalonyl-CoA Epimerase
Chromosome: CHR2: 71336805 -71357394
Locus: 2p13.3
Gene Diseases
The MCEE ANXA4 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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