MCC-PSMD6 Fusion FISH Probe
The MCC-PSMD6 Fusion FISH Probe is used to confirm a fusion of the MCC and PSMD6 genes. The fusion of the MCC and PSMD6 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MCC-PSMD6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MCC-PSMD6-20-AQAQ | 20 (40 μL) | 200 μL |
|
MCC Gene Summary
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Mutated In Colorectal Cancers
Chromosome: CHR5: 112357795 -112824527
Locus: 5q22.2
PSMD6 Gene Summary
This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012]
Gene Name: Proteasome 26S Subunit, Non-ATPase 6
Chromosome: CHR3: 63996230 -64009120
Locus: 3p14.1
Gene Diseases
The MCC PSMD6 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|