MBNL2-PLAC8 Fusion FISH Probe
The MBNL2-PLAC8 Fusion FISH Probe is used to confirm a fusion of the MBNL2 and PLAC8 genes. The fusion of the MBNL2 and PLAC8 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MBNL2-PLAC8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-RERE | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-REOR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-REGO | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-REGR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-REAQ | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-ORRE | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-OROR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-ORGO | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-ORAQ | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GORE | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GOOR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GOGO | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GOGR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GOAQ | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GRRE | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GROR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GRGO | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GRGR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-GRAQ | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-AQRE | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-AQOR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-AQGO | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-AQGR | 20 (40 μL) | 200 μL |
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| MBNL2-PLAC8-20-AQAQ | 20 (40 μL) | 200 μL |
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MBNL2 Gene Summary
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]
Gene Name: Muscleblind Like Splicing Regulator 2
Chromosome: CHR13: 97874573 -98046374
Locus: 13q32.1
PLAC8 Gene Summary
The Placenta Specific 8 (PLAC8) gene is located on chr4 :84011210-84035911 at 4q21.22.
Gene Name: Placenta Specific 8
Chromosome: CHR4: 84011210 -84035911
Locus: 4q21.22
Gene Diseases
The MBNL2 PLAC8 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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