MBNL2-HS6ST3 Fusion FISH Probe
The MBNL2-HS6ST3 Fusion FISH Probe is used to confirm a fusion of the MBNL2 and HS6ST3 genes. The fusion of the MBNL2 and HS6ST3 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MBNL2-HS6ST3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-RERE | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-REOR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-REGO | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-REGR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-REAQ | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-ORRE | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-OROR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-ORGO | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-ORAQ | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GORE | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GOOR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GOGO | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GOGR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GOAQ | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GRRE | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GROR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GRGO | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GRGR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-GRAQ | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-AQRE | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-AQOR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-AQGO | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-AQGR | 20 (40 μL) | 200 μL |
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| MBNL2-HS6ST3-20-AQAQ | 20 (40 μL) | 200 μL |
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MBNL2 Gene Summary
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]
Gene Name: Muscleblind Like Splicing Regulator 2
Chromosome: CHR13: 97874573 -98046374
Locus: 13q32.1
HS6ST3 Gene Summary
Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000 [PubMed 10644753]).[supplied by OMIM, Mar 2008]
Gene Name: Heparan Sulfate 6-O-sulfotransferase 3
Chromosome: CHR13: 96743092 -97491812
Locus: 13q32.1
Gene Diseases
The MBNL2 HS6ST3 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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