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MBNL1-SGSM3 Fusion FISH Probe

The MBNL1-SGSM3 Fusion FISH Probe is used to confirm a fusion of the MBNL1 and SGSM3 genes. The fusion of the MBNL1 and SGSM3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MBNL1-SGSM3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MBNL1-SGSM3-20-RERE 20 (40 μL) 200 μL
MBNL1-SGSM3-20-REOR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-REGO 20 (40 μL) 200 μL
MBNL1-SGSM3-20-REGR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-REAQ 20 (40 μL) 200 μL
MBNL1-SGSM3-20-ORRE 20 (40 μL) 200 μL
MBNL1-SGSM3-20-OROR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-ORGO 20 (40 μL) 200 μL
MBNL1-SGSM3-20-ORAQ 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GORE 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GOOR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GOGO 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GOGR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GOAQ 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GRRE 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GROR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GRGO 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GRGR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-GRAQ 20 (40 μL) 200 μL
MBNL1-SGSM3-20-AQRE 20 (40 μL) 200 μL
MBNL1-SGSM3-20-AQOR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-AQGO 20 (40 μL) 200 μL
MBNL1-SGSM3-20-AQGR 20 (40 μL) 200 μL
MBNL1-SGSM3-20-AQAQ 20 (40 μL) 200 μL

MBNL1 Gene Summary

This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]

Gene Name: Muscleblind Like Splicing Regulator 1

Chromosome: CHR3: 151985828 -152183568

Locus: 3q25.1-q25.2

SGSM3 Gene Summary

The Small G Protein Signaling Modulator 3 (SGSM3) gene is located on chr22 :40766594-40806293 at 22q13.1.

Gene Name: Small G Protein Signaling Modulator 3

Chromosome: CHR22: 40766594 -40806293

Locus: 22q13.1

Gene Diseases

The MBNL1 SGSM3 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.