MATR3-CTNNA1 Fusion FISH Probe
The MATR3-CTNNA1 Fusion FISH Probe is used to confirm a fusion of the MATR3 and CTNNA1 genes. The fusion of the MATR3 and CTNNA1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MATR3-CTNNA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-RERE | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-REOR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-REGO | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-REGR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-REAQ | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-ORRE | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-OROR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-ORGO | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GORE | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GOOR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GOGO | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GOGR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GRRE | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GROR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GRGO | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GRGR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-AQRE | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-AQOR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-AQGO | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-AQGR | 20 (40 μL) | 200 μL |
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| MATR3-CTNNA1-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNNA1 Gene Summary
This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]
Gene Name: Catenin Alpha 1
Chromosome: CHR5: 138089106 -138270723
Locus: 5q31.2
MATR3 Gene Summary
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013]
Gene Name: Matrin 3
Chromosome: CHR5: 138609440 -138667366
Locus: 5q31.2
Gene Diseases
The MATR3 CTNNA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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