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MAST4-MRPS27 Fusion FISH Probe

The MAST4-MRPS27 Fusion FISH Probe is used to confirm a fusion of the MAST4 and MRPS27 genes. The fusion of the MAST4 and MRPS27 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MAST4-MRPS27-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MAST4-MRPS27-20-RERE 20 (40 μL) 200 μL
MAST4-MRPS27-20-REOR 20 (40 μL) 200 μL
MAST4-MRPS27-20-REGO 20 (40 μL) 200 μL
MAST4-MRPS27-20-REGR 20 (40 μL) 200 μL
MAST4-MRPS27-20-REAQ 20 (40 μL) 200 μL
MAST4-MRPS27-20-ORRE 20 (40 μL) 200 μL
MAST4-MRPS27-20-OROR 20 (40 μL) 200 μL
MAST4-MRPS27-20-ORGO 20 (40 μL) 200 μL
MAST4-MRPS27-20-ORAQ 20 (40 μL) 200 μL
MAST4-MRPS27-20-GORE 20 (40 μL) 200 μL
MAST4-MRPS27-20-GOOR 20 (40 μL) 200 μL
MAST4-MRPS27-20-GOGO 20 (40 μL) 200 μL
MAST4-MRPS27-20-GOGR 20 (40 μL) 200 μL
MAST4-MRPS27-20-GOAQ 20 (40 μL) 200 μL
MAST4-MRPS27-20-GRRE 20 (40 μL) 200 μL
MAST4-MRPS27-20-GROR 20 (40 μL) 200 μL
MAST4-MRPS27-20-GRGO 20 (40 μL) 200 μL
MAST4-MRPS27-20-GRGR 20 (40 μL) 200 μL
MAST4-MRPS27-20-GRAQ 20 (40 μL) 200 μL
MAST4-MRPS27-20-AQRE 20 (40 μL) 200 μL
MAST4-MRPS27-20-AQOR 20 (40 μL) 200 μL
MAST4-MRPS27-20-AQGO 20 (40 μL) 200 μL
MAST4-MRPS27-20-AQGR 20 (40 μL) 200 μL
MAST4-MRPS27-20-AQAQ 20 (40 μL) 200 μL

MRPS27 Gene Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013]

Gene Name: Mitochondrial Ribosomal Protein S27

Chromosome: CHR5: 71515235 -71616084

Locus: 5q13.2

MAST4 Gene Summary

This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]

Gene Name: Microtubule Associated Serine/threonine Kinase Family Member 4

Chromosome: CHR5: 65892175 -66465423

Locus: 5q12.3

Gene Diseases

The MAST4 MRPS27 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.