MAST2-MMACHC Fusion FISH Probe
The MAST2-MMACHC Fusion FISH Probe is used to confirm a fusion of the MAST2 and MMACHC genes. The fusion of the MAST2 and MMACHC genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAST2-MMACHC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-RERE | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-REOR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-REGO | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-REGR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-REAQ | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-ORRE | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-OROR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-ORGO | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GORE | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GOOR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GOGO | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GOGR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GRRE | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GROR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GRGO | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GRGR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-AQRE | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-AQOR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-AQGO | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-AQGR | 20 (40 μL) | 200 μL |
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| MAST2-MMACHC-20-AQAQ | 20 (40 μL) | 200 μL |
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MAST2 Gene Summary
The Microtubule Associated Serine/threonine Kinase 2 (MAST2) gene is located on chr1 :46269284-46501796 at 1p34.1.
Gene Name: Microtubule Associated Serine/threonine Kinase 2
Chromosome: CHR1: 46269284 -46501796
Locus: 1p34.1
MMACHC Gene Summary
The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. [provided by RefSeq, Oct 2009]
Gene Name: Methylmalonic Aciduria (cobalamin Deficiency) CblC Type, With Homocystinuria
Chromosome: CHR1: 45965855 -45976739
Locus: 1p34.1
Gene Diseases
The MAST2 MMACHC Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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