MAST2-COQ6 Fusion FISH Probe
The MAST2-COQ6 Fusion FISH Probe is used to confirm a fusion of the MAST2 and COQ6 genes. The fusion of the MAST2 and COQ6 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAST2-COQ6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-RERE | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-REOR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-REGO | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-REGR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-REAQ | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-ORRE | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-OROR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-ORGO | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GORE | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GOOR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GOGO | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GOGR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GRRE | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GROR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GRGO | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GRGR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-AQRE | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-AQOR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-AQGO | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-AQGR | 20 (40 μL) | 200 μL |
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| MAST2-COQ6-20-AQAQ | 20 (40 μL) | 200 μL |
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MAST2 Gene Summary
The Microtubule Associated Serine/threonine Kinase 2 (MAST2) gene is located on chr1 :46269284-46501796 at 1p34.1.
Gene Name: Microtubule Associated Serine/threonine Kinase 2
Chromosome: CHR1: 46269284 -46501796
Locus: 1p34.1
COQ6 Gene Summary
The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2012]
Gene Name: Coenzyme Q6, Monooxygenase
Chromosome: CHR14: 74416636 -74429813
Locus: 14q24.3
Gene Diseases
The MAST2 COQ6 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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