MASP2-EXOSC10 Fusion FISH Probe
The MASP2-EXOSC10 Fusion FISH Probe is used to confirm a fusion of the MASP2 and EXOSC10 genes. The fusion of the MASP2 and EXOSC10 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MASP2-EXOSC10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-RERE | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-REOR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-REGO | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-REGR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-REAQ | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-ORRE | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-OROR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-ORGO | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-ORAQ | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GORE | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GOOR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GOGO | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GOGR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GOAQ | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GRRE | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GROR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GRGO | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GRGR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-GRAQ | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-AQRE | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-AQOR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-AQGO | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-AQGR | 20 (40 μL) | 200 μL |
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| MASP2-EXOSC10-20-AQAQ | 20 (40 μL) | 200 μL |
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EXOSC10 Gene Summary
The Exosome Component 10 (EXOSC10) gene is located on chr1 :11126675-11159938 at 1p36.22.
Gene Name: Exosome Component 10
Chromosome: CHR1: 11126675 -11159938
Locus: 1p36.22
MASP2 Gene Summary
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Name: Mannan Binding Lectin Serine Peptidase 2
Chromosome: CHR1: 11086579 -11107296
Locus: 1p36.22
Gene Diseases
The MASP2 EXOSC10 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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