MARVELD2-WDR19 Fusion FISH Probe
The MARVELD2-WDR19 Fusion FISH Probe is used to confirm a fusion of the MARVELD2 and WDR19 genes. The fusion of the MARVELD2 and WDR19 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MARVELD2-WDR19-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-RERE | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-REOR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-REGO | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-REGR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-REAQ | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-ORRE | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-OROR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-ORGO | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-ORAQ | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GORE | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GOOR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GOGO | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GOGR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GOAQ | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GRRE | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GROR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GRGO | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GRGR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-GRAQ | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-AQRE | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-AQOR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-AQGO | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-AQGR | 20 (40 μL) | 200 μL |
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| MARVELD2-WDR19-20-AQAQ | 20 (40 μL) | 200 μL |
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WDR19 Gene Summary
The protein encoded by this gene is a member of the WD (tryptophan-aspartic acid) repeat family, which is a large family of structurally-related proteins known to participate in a wide range of cellular processes. Each WD repeat typically contains about 40 amino acids that are usually bracketed by glycine-histidine and tryptophan-aspartic acid (WD) dipeptides. This protein contains six WD repeats, three transmembrane domains, and a clathrin heavy-chain repeat. Mutations in this gene have been described in individuals with a wide range of disorders affecting function of the cilium. These disorders are known as ciliopathies, and include Jeune syndrome, Sensenbrenner syndromes, Senior-Loken syndrome, combined or isolated nephronophthisis (NPHP), and retinitis pigmentosa (RP). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Name: WD Repeat Domain 19
Chromosome: CHR4: 39184023 -39287430
Locus: 4p14
MARVELD2 Gene Summary
The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: MARVEL Domain Containing 2
Chromosome: CHR5: 68710938 -68737890
Locus: 5q13.2
Gene Diseases
The MARVELD2 WDR19 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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