MARVELD2-PIK3R1 Fusion FISH Probe
The MARVELD2-PIK3R1 Fusion FISH Probe is used to confirm a fusion of the MARVELD2 and PIK3R1 genes. The fusion of the MARVELD2 and PIK3R1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MARVELD2-PIK3R1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-RERE | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-REOR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-REGO | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-REGR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-REAQ | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-ORRE | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-OROR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-ORGO | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GORE | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GOOR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GOGO | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GOGR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GRRE | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GROR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GRGO | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GRGR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-AQRE | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-AQOR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-AQGO | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-AQGR | 20 (40 μL) | 200 μL |
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| MARVELD2-PIK3R1-20-AQAQ | 20 (40 μL) | 200 μL |
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PIK3R1 Gene Summary
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Gene Name: Phosphoinositide-3-kinase Regulatory Subunit 1
Chromosome: CHR5: 67511583 -67597649
Locus: 5q13.1
MARVELD2 Gene Summary
The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: MARVEL Domain Containing 2
Chromosome: CHR5: 68710938 -68737890
Locus: 5q13.2
Gene Diseases
The MARVELD2 PIK3R1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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