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MARK3-EIF5 Fusion FISH Probe

The MARK3-EIF5 Fusion FISH Probe is used to confirm a fusion of the MARK3 and EIF5 genes. The fusion of the MARK3 and EIF5 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MARK3-EIF5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MARK3-EIF5-20-RERE 20 (40 μL) 200 μL
MARK3-EIF5-20-REOR 20 (40 μL) 200 μL
MARK3-EIF5-20-REGO 20 (40 μL) 200 μL
MARK3-EIF5-20-REGR 20 (40 μL) 200 μL
MARK3-EIF5-20-REAQ 20 (40 μL) 200 μL
MARK3-EIF5-20-ORRE 20 (40 μL) 200 μL
MARK3-EIF5-20-OROR 20 (40 μL) 200 μL
MARK3-EIF5-20-ORGO 20 (40 μL) 200 μL
MARK3-EIF5-20-ORAQ 20 (40 μL) 200 μL
MARK3-EIF5-20-GORE 20 (40 μL) 200 μL
MARK3-EIF5-20-GOOR 20 (40 μL) 200 μL
MARK3-EIF5-20-GOGO 20 (40 μL) 200 μL
MARK3-EIF5-20-GOGR 20 (40 μL) 200 μL
MARK3-EIF5-20-GOAQ 20 (40 μL) 200 μL
MARK3-EIF5-20-GRRE 20 (40 μL) 200 μL
MARK3-EIF5-20-GROR 20 (40 μL) 200 μL
MARK3-EIF5-20-GRGO 20 (40 μL) 200 μL
MARK3-EIF5-20-GRGR 20 (40 μL) 200 μL
MARK3-EIF5-20-GRAQ 20 (40 μL) 200 μL
MARK3-EIF5-20-AQRE 20 (40 μL) 200 μL
MARK3-EIF5-20-AQOR 20 (40 μL) 200 μL
MARK3-EIF5-20-AQGO 20 (40 μL) 200 μL
MARK3-EIF5-20-AQGR 20 (40 μL) 200 μL
MARK3-EIF5-20-AQAQ 20 (40 μL) 200 μL

EIF5 Gene Summary

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]

Gene Name: Eukaryotic Translation Initiation Factor 5

Chromosome: CHR14: 103800492 -103811361

Locus: 14q32.32

MARK3 Gene Summary

The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Gene Name: Microtubule Affinity Regulating Kinase 3

Chromosome: CHR14: 103851700 -103970166

Locus: 14q32.32-q32.33

Gene Diseases

The MARK3 EIF5 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.