MARK3-EIF5 Fusion FISH Probe
The MARK3-EIF5 Fusion FISH Probe is used to confirm a fusion of the MARK3 and EIF5 genes. The fusion of the MARK3 and EIF5 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MARK3-EIF5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-RERE | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-REOR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-REGO | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-REGR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-REAQ | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-ORRE | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-OROR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-ORGO | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-ORAQ | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GORE | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GOOR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GOGO | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GOGR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GOAQ | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GRRE | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GROR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GRGO | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GRGR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-GRAQ | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-AQRE | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-AQOR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-AQGO | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-AQGR | 20 (40 μL) | 200 μL |
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| MARK3-EIF5-20-AQAQ | 20 (40 μL) | 200 μL |
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EIF5 Gene Summary
Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]
Gene Name: Eukaryotic Translation Initiation Factor 5
Chromosome: CHR14: 103800492 -103811361
Locus: 14q32.32
MARK3 Gene Summary
The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Microtubule Affinity Regulating Kinase 3
Chromosome: CHR14: 103851700 -103970166
Locus: 14q32.32-q32.33
Gene Diseases
The MARK3 EIF5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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